PK11007 190x100mm

PK11007 190x100mmPK11007 is an anti p53 drug that stabilizes wild type and mutant p53 via selective alkylation of two surface exposed cysteines without compromising its DNA binding activity. It exerts antitumor functions not only via reactivating p53 but also via other cellular mechanisms, such as increase of cellular ROS to toxic levels and activation of the UPR.

MI-136 can specifically inhibit the menin-MLL interaction

beta-lactamase-stable cephalosporin with antibacterial activity

FPS-ZM1 is a blood-brain-barrier permeant

~10-fold more selective for VEGFR than PDGFR and Ret

a naturally occurring eudesmane-type sesquiterpene lactone (SL)

Nazartinib (EGF816

The data is registered in 5 databases: operators (up to 10 users)

has a modest affinity for recombinant estrogen receptor ER

9 nM and 11

It also inhibits GSK3

the sweet food additive extracted from the plant Stevia Rebaudiana Bertoni (Bertoni)

Corning These 50mL PYREX® low form weighing bottles have a 60/12 Standard Taper joint style opening that accepts a closed bottom