PIM447 (LGH447) Square Glass Media Storage Bottles

PIM447 (LGH447) Square Glass Media Storage BottlesPIM447 is a novel pan PIM kinase inhibitor with Ki values of 6 pM, 18 pM, 9 pM for PIM1, PIM2, PIM3 respectively. It also inhibits GSK3?, PKN1, and PKC?, but at a significantly lower potency with IC50 between 1 and 5 ? M (>105 fold differential relative to the Ki on PIMs).

-induced IKK activity

Mubritinib (TAK-165) is a potent inhibitor of HER2/ErbB2 with IC50 of 6 nM in BT-474 cell

Corning These flat PYREX® dishes have approximately a 740mL capacity with rims that are reinforced and fire polished to reduce chipping

5 nM and 4 nM for RSK1

such as inhibition of calcium influx through both voltage and receptor-operated channels and inhibition of rabbit blood platelet aggregation

58-fold more selective for PI3K

inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 of 5 nM and 30 nM in C2C12 cells

SC79 is a brain-penetrable Akt phosphorylation activator and an inhibitor of Akt-PH domain translocation

interfering with the ability of bacteria to produce essential proteins

with the same polymeric structure as sevelamer hydrochloride

non-steroidal

StemRegenin 1 is an aryl hydrocarbon receptor (AhR) inhibitor with IC50 of 127 nM in a cell-free assay